Bone Marrow Transplantation
Bone marrow transplantation (also known as stem cell transplantation) involves harvesting healthy stem cells to replenish the bone marrow of the patient. The new stem cells take over the production of the blood cells.
In some circumstances, it may be possible to take your own bone marrow body (this is known as autologous transplantation) and also to take stem cells from related or unrelated donor.
Stages of The Transplant Process
- A physical examination of patient and general state of health;
- Stimulation and mobilization stem cells which be use at the process of transplantation;
- Preparing the patient for the transplant (known as conditioning);
- Transplanting the stem cells;
- The recovery period, during which patient will be monitored for 100 days (in sterile room about 30 days) for any side effects and complications.
Why Bone Marrow Transplants Are Necessary?
Stem cell transplantations are often required to treat conditions that have damaged the bone marrow which, as a result, can no longer produce normal blood cells. Any disruption to the production of blood cells can be very serious:
- Lymphoma (HDL, HL);
- Multiple myeloma (MM);
- Hereditary blood disorders (thalassemia e.t.c);
- Acquired blood disorders (SAA e.t.c);
- Solid tumors;
- Genetic disorder of metabolism.
Who Can Have A Bone Marrow Transplant?
Patient with complete remission;
Patient with partial remission;
The associated condition is not responding to other forms of treatment or it is felt that there is a high risk of the condition returning without a transplant;
Hereditary disorders disease progression if the patient has compatible donor.